Xanthatin-13-(Pyrrolidine-2-Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ<sub>25-35</sub> Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease.

The XPc treatment, at 1 mg/kg IP, failed to affect GFAP IF in all three areas, although a decreasing trend was noted in PoDG ( p = 0.052 vs.

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Aβ 25‐35 ‐treated mice indeed showed a highly significant deficit in spontaneous alternation that was prevented by the 4‐days treatment with XPc at the doses of 1 and 3 mg/kg IP (Figure 1B ).

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