Barely Significant
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Biological use of molybdenum and tungsten stems back to 3.4 billion years ago.

Nat Commun · 2026 · PMC13144720 · PMID 42086593

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an overall trendno p-value reported
This observation may be specific to molybdoenzymes or potentially reflect an overall trend in the rise of oxidoreductases alongside changes in atmospheric oxygen levels.

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