Efficacy of Dextromethorphan Augmentation in SSRI-Resistant Obsessive-Compulsive Disorder: A Randomized Controlled Trial.

Health Sci Rep · 2026 · PMC13144750 · PMID 42100757

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

Importantly, the time × group interaction was highly significant (F (1.455, df) = 74.324, p < 0.001, partial eta squared = 0.662), indicating that the pattern of change differed between the two groups.

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a numerical trendno p-value reported

(2015) evaluated riluzole as an adjunct to serotonin reuptake inhibitors (SRIs) but failed to show statistically significant superiority over placebo despite a numerical trend favoring riluzole [ 28 ].

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