Genetic variation in innate immune gene expression influences mortality after traumatic brain injury in Drosophila.

G3 (Bethesda) · 2026 · PMC13148387 · PMID 41823481

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0790

boldest claim

The sentences

highly significantP = 4.58 × 10 −7actually significant

An analysis of gene expression considering all genes and DGRP lines revealed a highly significant five-way interaction among injury, diet, age, gene, and line (ANOVA, F 144,2736 = 1.72, P = 4.58 × 10 −7 ), with interaction meaning that the effect of one factor on gene expression depends on the level(s) or one or more other factors.

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marginally nonsignificantP = 0.079so close (0.05 < p ≤ 0.1)

8 ), where the result was marginally nonsignificant ( P = 0.079).

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