highly significantp < 0.01
To visualize the most pronounced effects that exposure to CO 2 had on gene expression, we constructed a heatmap of common highly significant DEGs (p < 0.01) of the two CO 2 comparisons and plotted the average fragments per kilobase of transcript per million fragments mapped (FPKM) values of each experimental group (Fig. 2 c, Supplementary Information S4 ).