Heterogeneous Biological Responses to Low-Level Sodium Saccharin Exposure: An Integrated Computational Toxicology and Mendelian Randomization Study.

Dose Response · 2026 · PMC13153579 · PMID 42111489

Europe PMC DOI

hedged sentence

0.0440

closest p · 0.9× alpha

0.0440

boldest claim

The sentences

marginal significanceP = 0.044actually significant

12 The positive association with Kaposi sarcoma (OR = 3.73) in this study, though with a wide confidence interval and marginal significance ( P = 0.044), along with protective associations for skin and colon cancers, highlights that health effects may depend heavily on cancer type and exposure context.

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