Association of a novel triglyceride-glucose and non-HDL-to-HDL cholesterol ratio (TyG-NHHR) index with cardiometabolic multimorbidity: a dual-cohort prospective study in Chinese and European adults.

J Health Popul Nutr · 2026 · PMC13154508 · PMID 41906188

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highly significantno p-value reported

The analysis revealed that the pathway from TyG to CMM through NHHR was not significant, with NHHR mediating a negligible and non-significant proportion of the total effect (4.4%, 95% CI: −2.7% to 9.9%).Conversely, the reverse pathway was highly significant.

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