PARG inhibition in ATM-deficient prostate cancer: from mechanistic discovery to therapeutic potential.

J Transl Med · 2026 · PMC13154661 · PMID 42092965

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a slight trendno p-value reported

Although there was a slight trend toward a reduction in NAD+ levels in ATM-KO cells, no significant reduction in NAD+ levels was detected in either ATM-KO or WT cells after PARGi treatment (Supplementary Fig. 2 D).

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