a trend towards significancep = 0.053
In univaraible analysis by TNM8-cN category, worse PFS with iENE-positive vs iENE-negative were observed among cN1 patients (HR, 5.51, 95% CI: 1.55–19.53, p = 0.008), and a trend towards significance in cN2 patients (HR, 9.74, 95% CI: 0.97–97.96, p = 0.053).