Barely Significant
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Missense substitutions in the BTB domain of ZBTB24 can lead to protein instability and cause ICF2 syndrome.

Hum Mol Genet · 2026 · PMC13158236 · PMID 41359419

1
hedged sentence
0.0420
closest p · 0.8× alpha
0.0420
boldest claim

The sentences

borderline significantP value = 0.042actually significant
Analyses of ZBTB24 mRNA levels demonstrated that SZ LCLs express normal levels, while in RZ LCLs the levels were reduced at a borderline significant level (P value = 0.042, Fig. 4C ).

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