Coagulation protease-activated receptor-2 (PAR2) promotes dyslipidemia, obesity and MASLD through repression of the hepatic pioneer factor HNF4α.

JHEP Rep · 2026 · PMC13158410 · PMID 42092280

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0.0002

closest p · 0.0× alpha

0.0002

boldest claim

The sentences

highly significantp = 0.0002actually significant

1 B, there was a highly significant correlation (R = 0.74, p = 0.0002) between body weight and liver PAR2 expression in PAR2 ΔHep mice vs. wild-type (WT; PAR2 fl/fl ).

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