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Estimating the nationwide incidence of coxsackievirus A6-associated hand, foot and mouth disease in China, 2008-2022.

Infect Dis Poverty · 2026 · PMC13159216 · PMID 42116129

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an increasing trendno p-value reported
The proportion of HFMD outbreaks caused by CV-A6 has also shown an increasing trend nationwide, with approximately 17.05% of outbreaks attributable to CV-A6 following the introduction of the EV-A71 vaccine [ 12 ].

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