Tc-99m DMSA Radiomics in CKD: Phenotype-Specific Cortical Signatures and a Morphological Predictor of Renal Function Decline.

In a two-variable adjusted model combining Centre of Mass Shift and Voxels Counting (EPV = 22.0; C-index: 0.641), Centre of Mass Shift retained a consistent directional effect (HR: 0.79; 95% CI: 0.62–1.02; p = 0.067), while Voxels Counting reached statistical significance (HR: 0.71; 95% CI: 0.55–0.93; p = 0.011); the borderline significance of Centre of Mass Shift in the adjusted setting likely reflects reduced statistical power rather than loss of the underlying signal.

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