Celastrol Ameliorates Renal Injury in Spontaneously Hypertensive Rats by Activating the Nrf2/Ho-1 Signaling Pathway to Alleviate Oxidative Stress.

Int J Mol Sci · 2026 · PMC13164436 · PMID 42123434

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

highly significantp ≤ 0.01actually significant

In both L-CSL groups, the mRNA levels of Nrf2 and Nqo1 were significantly higher than those in the SHR group ( p ≤ 0.01), with a highly significant difference between the two CSL doses ( p ≤ 0.01).

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