Correlation of bone metabolism serum markers with clinical parameters of the disease progression during 2-year follow-up in patients with chronic obstructive pulmonary disease.

Tzu Chi Med J · 2026 · PMC13167094 · PMID 42131410

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0980

boldest claim

The sentences

at the limit of significanceP = 0.054so close (0.05 < p ≤ 0.1)

10.85 ± 1.68 ng/mL, P = 0.035 Figure 2 ] and had weak negative correlation with FEV1% at the beginning, at the limit of significance (Rho = −0.254, P = 0.054) and at the end of the follow-up period (Rho = −0.296, P = 0.028).

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a reliable trendP = 0.055so close (0.05 < p ≤ 0.1)

There was a reliable trend for negative correlation of serum 25(OH) D 3 with the number of exacerbations during the study period (Rho = −0.291, P = 0.055) and a significant positive correlation with FEV1% predicted (Rho = 0.728, P = 0.003) but only in patients with advanced stages.

also in 67 other papers

close to being statistically significantP = 0.055so close (0.05 < p ≤ 0.1)

The serum 25(OH)D 3 negatively correlated with the number of exacerbations during the study period close to being statistically significant (Rho = −0.291, P = 0.055) in patients with advanced GOLD stages (GOLD III and GOLD IV) (Rho = −0.291, P = 0.055) and patients in Group E according to ABE classification (Rho = 0.872, P = 0.054).

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a slight trendP = 0.098so close (0.05 < p ≤ 0.1)

A positive correlation of OPN with the spirometric lung function indexes FEV1/FVC% at the beginning (Rho = 0.276, P = 0.041) and a slight trend toward significant correlation with FEV1% predicted at the end of the study period (Rho = 0.232, P = 0.098) were found.

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