Nutritional properties of extracellular vesicle-like particles from <i>Sophora flavescens</i> and <i>Periplaneta americana</i> with effects on streptozotocin-induced diabetic wound healing in rats.

Furthermore, compared with the model group, blood glucose levels in the treatment groups showed a decreasing trend, suggesting that SF-PA-EVLPs exerts a regulatory effect on blood glucose levels in diabetic rats. 2.8 SF-PA-EVLPs have negligible effects on bone formation in diabetic wound model rats The development of diabetogenic osteoporosis is closely associated with a chronic hyperglycemic microenvironment ( 20 ).

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