Distinct mutational landscape and clonal evolution of POLE-mutated endometrial cancer: geographic variation and insights into multiple classifier status.

J Transl Med · 2026 · PMC13170004 · PMID 42062848

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hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

a marginal trendp = 0.080so close (0.05 < p ≤ 0.1)

However, a marginal trend toward a higher rate of lymph node metastasis was observed in the P286R group compared to the V411L group (15.6% [10/64] vs. 5.2% [3/58], p = 0.080).

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