Preemptive cardioprotection with a small molecule in rodents that suppresses genes predictive of heart failure.

Sci Adv · 2026 · PMC13170658 · PMID 42127187

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highly significantno p-value reported

In STARNET, EGR1 and ATF3 are highly significant for DUKE CAD severity score (which predicts all-cause mortality) and JUN correlates with SYNTAX (Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) risk score (predictive of MACE) ( Fig. 8A ).

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