PON1 (Paraoxonase 1) Q192R Gene Polymorphism in North Macedonian Population with Confirmed Coronary Artery Disease.

A meta-analysis documented that the Q192R polymorphism is the only genetic variant in the PON1 gene that confers a highly significant, albeit small (7% per R allele), risk for coronary artery disease [ 22 ] and another independent meta-analysis estimated a 10% higher risk for carriers of the R allele [ 23 ].

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