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Development of coumarin-sulfonate scaffolds for cholinesterase inhibition: experimental and computational studies toward Alzheimer's disease therapy.

RSC Adv · 2026 · PMC13178244 · PMID 42148273

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a definite trendno p-value reported
Electronic effects of para substituents The para -substituted derivatives (1, 2, 5, and 9) all exhibited a definite trend where the electron-donating character of these groups increased the AChE inhibition.

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