Effect of Perioperative Ketamine on Early Postpartum Depressive Symptoms Following Cesarean Section: A Meta-Analysis.

Cureus · 2026 · PMC13179825 · PMID 42147527

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modestly significantno p-value reported

Discussion In this meta-analysis of six RCTs, perioperative ketamine or esketamine exposure during cesarean section was associated with modestly significant lower EPDS scores compared to control between POD 3 and 14.

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