borderline significancep= 0.059
While the allelic association of SNP rs4681767 showed borderline significance in the overall cohort (0.459 vs 0.336, OR 1.680, 95% CI 0.989-2.854, p= 0.059), a statistically significant association was observed in the SPS type II subgroup (0.535 vs 0.336, OR 2.272, 95% CI 1.217-4.240, p=0.011) ( Table 1 ).