On the other hand, tocilizumab has demonstrated efficacy in the treatment of acute GVHD ( 40 ), and, in a phase III trial, showed a nonsignificant trend toward lower incidence of grade II-IV aGVHD In the HLA-matched unrelated donor transplant setting ( 41 ).
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Cytokine release syndrome after allogeneic hematopoietic stem cell transplantation using posttransplant cyclophosphamide: current understanding and management.
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