The long-term mortality burden of childhood traumatic fractures: a mediation analysis of osteoarthritis and psychosocial pathways in older European adults.

Arch Public Health · 2026 · PMC13181883 · PMID 41872942

Europe PMC DOI

hedged sentences

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

marginally significantp = 0.089so close (0.05 < p ≤ 0.1)

OA had a marginally significant effect on SISA (β = 0.147, p = 0.089), and SISA significantly predicted mortality (β = 0.224, p < 0.001).

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marginal significanceno p-value reported

Significant indirect effects were observed through IADL (19.3%), EURO-D (27.5%, marginal significance), and SISA (31.9%), indicating that functional decline, depressive symptoms, and social isolation are important mechanisms contributing to elevated mortality.

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