Barely Significant
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Tourniquet, tranexamic acid, and computer-assisted cryotherapy in primary total knee arthroplasty: A retrospective cohort study.

Medicine (Baltimore) · 2026 · PMC13183136 · PMID 42152430

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highly significantno p-value reported
The substantial inter-group difference in diclofenac usage—highly significant in this analysis–suggests that cryotherapy may meaningfully reduce post-operative soft-tissue inflammation, thereby decreasing reliance on non-steroidal anti-inflammatory drugs.

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