highly significantp < 0.001
Statistical significance was determined based on p -values, with thresholds defined as follows: * p < 0.05 (statistically significant), ** p < 0.01 (highly significant), and *** p < 0.001 (very highly significant).
Statistical significance was determined based on p -values, with thresholds defined as follows: * p < 0.05 (statistically significant), ** p < 0.01 (highly significant), and *** p < 0.001 (very highly significant).