Barely Significant
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Effectiveness of Virtual Reality Interventions on Perioperative Anxiety, Depression, Blood Pressure, and Heart Rate: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

JMIR Serious Games · 2026 · PMC13188064 · PMID 42159282

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might not be significantno p-value reported
The 95% PI indicated that the effect of VR on depression was stable in most clinical settings, whereas its effects on anxiety, blood pressure, and heart rate were influenced by heterogeneity and might not be significant in some specific contexts.

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