EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk.

Nature · 2026 · PMC13190245 · PMID 41986726

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highly significantno p-value reported

In the discovery phase, the strongest interaction signal was observed at HLA-A amino acid position 62, where the presence of glutamine (A62Q) showed a highly significant interaction with high-risk EBV strains ( P interaction = 5.88 × 10 −12 ).

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