Effectiveness and safety of bone protective interventions to mitigate bone loss and skeletal fractures experienced by patients with non-metastatic breast cancer: a systematic review and meta-analysis.

Osteoporos Int · 2026 · PMC13190351 · PMID 41697310

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highly significantno p-value reported

On the contrary, whilst percentage change values were not provided, a slight decrease in TH BMD, although non-significant, was observed with ZA compared to a highly significant increase with denosumab [−0.001 g/cm 2 vs. 0.019 g/cm 2 [ 48 ]].

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