Unstable sleep and rest-activity rhythms in adolescents at-risk for bipolar disorder: Links to mood symptoms and the effect of sleep stabilization.

These findings are particularly important because familial risk is a highly significant predisposing factor for BD( Birmaher et al., 2009 ; Kessler et al., 2005 ), yet there are few modifiable targets to reduce risk or delay progression to the disorder.

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