Integrating multiomics to elucidate the role of chromatin remodeling in glioma and the antitumor mechanisms and therapeutic potential of targeting LMNA.

The two resulting subtypes (Subgroup 1 and Subgroup 2) were visually well-separated in the dimensionality reduction projection ( Figure 1G ) and exhibited a highly significant difference in overall survival ( Figure 1H ), with patients in Subgroup 2 experiencing markedly better outcomes.

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