Proton pump inhibitor exposure modulates functional and transcriptional responses in <i>Lactobacillus acidophilus</i>: a comprehensive computational and experimental insights.

Pantoprazole induced highly significant suppression across all genes at both 50 μg/mL and 100 μg/mL, with comparable p-values (p = 1.49 × 10 -8 ; BH-adjusted p = 1.49 × 10 -8 ), highlighting a consistent and substantial inhibitory action ( Figure 17a ).

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