Network pharmacology, molecular docking, and in vivo experiments reveal the effects of Polygonati Rhizoma on periodontitis.

Sci Rep · 2026 · PMC13194701 · PMID 41748638

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a decreasing trendno p-value reported

Additionally, the levels of IL-6 and TNF-α in the serum of the PD mice were significantly elevated ( P < 0.01), but these concentrations showed a decreasing trend after the administration of Polygonati Rhizoma (Fig. 7 C-D).

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