Barely Significant
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A multicenter randomized clinical trial of portable transcranial alternating current stimulation for major depressive disorder.

NPJ Digit Med · 2026 · PMC13194911 · PMID 41904320

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an overall trendno p-value reported
Other exploratory outcomes Although an overall trend of improvement in functional impairment was observed following the 4-week active HD-tACS intervention, reductions in Sheehan Disability Scale (SDS) domain scores, “work/school”, “social life”, and “family life” did not differ significantly between the active and sham groups (Supplementary Fig. 3 ).

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