Machine learning-driven multi-omics integration uncovers a senescence associated molecular axis in HCC.

Front Immunol · 2026 · PMC13195000 · PMID 42183188

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highly significantno p-value reported

The analysis confirmed that the RSF-derived risk score remained a highly significant and independent risk factor for overall survival (Hazard Ratio = 1.04, 95% CI: 1.01-1.06), unaffected by traditional clinical parameters ( Figure 2H ).

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