FOXA1 loss drives basal/squamous de-differentiation of prostate cancer and induces an immunosuppressive tumor microenvironment.

Nat Commun · 2026 · PMC13195071 · PMID 41904157

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an overall trendno p-value reported

Interestingly, our results revealed that FOXA1 expression was significantly negatively correlated with the abundance of various immune cell populations, supporting an overall trend towards increased immune cell accumulation in FOXA1 -low tumors (Fig. 7B ).

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