A systematic review of contemporary randomized controlled trials for treatment of lower extremity lymphedema by intermittent pneumatic compression devices.

J Vasc Surg Venous Lymphat Disord · 2026 · PMC13197773 · PMID 41997536

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highly significantno p-value reported

Conclusions Despite combining (bundling) additional treatment with IPC in three studies, intragroup comparisons demonstrated highly significant reductions in limb volumes with IPC in all RCTs and in five of seven RCTs by intergroup comparison.

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