Most amino acids and their derivatives exhibited a decreasing trend post-infection, likely reflecting the timing of kidney sample collection on day 7 post-infection—a late stage of viral infection during which the virus hijacks amino acids to facilitate replication.
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Avian coronaviruses induce inflammatory responses by activating p38/MAPK signaling and NLRP3/caspase-1 inflammasomes through sphingosine-1-phosphate receptor 1.
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