Multi-Omics profiling identify NNMT in tumor endothelium as a key regulator of CD8⁺ T cell exhaustion via the TGF signaling pathway.

Transl Oncol · 2026 · PMC13199851 · PMID 42140035

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highly significantno p-value reported

1D), while functional enrichment analysis provided an overview of highly significant association of endothelial cells with apoptosis pathways (Supplementary Fig. 1B).

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