Acute sildenafil administration decreases the susceptibility to induced atrial fibrillation in sheep.

J Mol Cell Cardiol Plus · 2026 · PMC13202541 · PMID 42206148

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borderline significancep = 0.05actually significant

Sildenafil tended to prolong the APD90, reaching borderline significance at longer cycle lengths (APD90 at 500 ms pacing 181.2 ± 8.7 ms vs 215.2 ± 17.0 ms; p = 0.05, overall p = 0.06 Fig. 2 Aiii).

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