5 , 14 This mechanism leads to a paradoxical phenomenon where certain euchromatic regions and TE boundaries undergo localized CHH hypermethylation, despite an overall trend of heterochromatin relaxation ( Table 2 ). 4 , 5 Furthermore, H1-mediated compaction is essential for preventing any aberrant Chromomethylase 2 (CMT2) activity, which would otherwise gain interactability with previously inaccessible regions within the genomes of h1 mutants. 5 ,
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Unveiling the epigenetic and stress-responsive function of histone H1 in plants.
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