Transcriptome Profiling of Induced Sputum Identified Upregulated TNF-α/NF-κB Signalling and Downregulated Mitochondrial Respiratory Chain Function in Post-Infectious Bronchiolitis Obliterans.

As expected, mIHC staining confirmed the highly significant increase in the total cell count (PiBO 129 ± 33 10 4 /mL; controls 58 ± 8 10 4 /mL; p < 0.05) and numbers of neutrophil granulocytes (PiBO 60 ± 21 10 4 /mL; controls 7.1 ± 1.3 10 4 /mL; p < 0.01) in patient sputum ( Figure 4 A,B).

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