marginally significantp = 0.06
A significant interaction was observed for smoking status ( p = 0.025), with the strongest effect in never-smokers (OR = 1.08, 95% CI: 1.06–1.09), and a marginally significant interaction was found for BRCA mutation status ( p = 0.06; carriers: OR = 1.15 vs. non-carriers: OR = 1.06).