Real-World Association of SGLT2 Inhibitors with Mortality in Very Elderly Patients with HFrEF and CKD.

Biomedicines · 2026 · PMC13204835 · PMID 42193308

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borderline significantno p-value reported

In our cohort of very elderly patients (mean age 85 years), a borderline significant reduction in mortality was shown.

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borderline significanceno p-value reported

We consider our result hypothesis-generating due to the borderline significance, yet of clinical relevance as it shows the potential benefits of SGLT2 inhibition with regard to reducing all-cause mortality in this cohort.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.