In addition, DMF reduced microgliosis and showed a decreasing trend in the levels of pro-inflammatory mediators cyclooxygenase-2 (COX-2) and NADPH oxidase 2 (NOS-2), as well as the glial markers GFAP, ionized calcium-binding adapter molecule 1 (IBA1), and major histocompatibility complex II (MHCII).
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The Emerging Role of Dimethyl Fumarate in Alzheimer's Disease-A Systematic Review of Available Preclinical Studies.
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