The APOA1-SNCA Axis as a Molecular Bridge Between CKD and Parkinson's Disease: A Systems Biology Model of Kidney-to-Brain Propagation via Exosomal Pathways.

Int J Mol Sci · 2026 · PMC13207088 · PMID 42196160

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

Functional enrichment analysis revealed a highly significant and specific convergence: the “Amyloid fiber formation” pathway (Reactome: HSA-977225; false discovery rate (FDR) = 0.0381, Strength = 2.41) was the top hit.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.