Left Atrial Appendage Occlusion Versus Direct Oral Anticoagulation in Atrial Fibrillation Patients at Very High Risk of Stroke: A Budget Impact Analysis in Italy.

J Clin Med · 2026 · PMC13207641 · PMID 42194650

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In some instances, namely for stroke, the costs related to informal care and productivity losses represent a highly significant burden on lifetime costs [ 67 ].

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