Comprehensive Analysis of Atrial Fibrillation/Atrial Flutter Burden in the United States and the European Union: A Comparison and Assessment of Trends and Risk Factors.

The estimated annual percentage change (EAPC) was calculated by fitting a linear regression model to the natural logarithm of the ASR: y = α + β x + ε y = l n [ A S R ] x = c a l e n d a r y e a r E A P C = 100 ( e β − 1 ) An increasing trend was defined as an EAPC with a 95% CI entirely above zero; a decreasing trend as a 95% CI entirely below zero.

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Although the absolute number of deaths does remain low, these numbers point to a worrying trend.

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The estimated annual percentage change (EAPC) was calculated by fitting a linear regression model to the natural logarithm of the ASR: y = α + β x + ε y = l n [ A S R ] x = c a l e n d a r y e a r E A P C = 100 ( e β − 1 ) An increasing trend was defined as an EAPC with a 95% CI entirely above zero; a decreasing trend as a 95% CI entirely below zero.

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