The Caffeinated Brain Part 1: The Effects of Caffeine on Event-Related Potentials (ERPs)-A Systematic and Mechanistic Review.

In children diagnosed as hyperkinetic, caffeine produced a clear, dose-related attenuation of the N140-P200 evoked response amplitude, most reliably at occipital sites: as caffeine dose increased (placebo → ~3 mg/kg → ~6 mg/kg), the evoked response became smaller, with particularly strong reductions at O2 (highly significant) and a weaker but still significant reduction at O1, alongside a more limited right-parietal effect at P4 [ 48 ].

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