CSF Levels of Baseline VCAM-1 and ICAM-1 Are Associated with Tau Pathology in Patients Demonstrating Cognitive Impairment.

Neurol Int · 2026 · PMC13210058 · PMID 42188684

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp = 2.5 × 10 −8actually significant

The frequency of APOE ε4 carriers increased progressively across the clinical spectrum, from CN individuals (25%) to those with MCI (53%) and AD (71%), with a highly significant group effect ( p = 2.5 × 10 −8 ). 3.1.

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